After everyone's favorite St. Bernard gets fired from a movie, Beethoven begins the long journey home with his trainer, Eddie. On their way, they become stranded in a small coastal town where the beloved canine befriends a young boy who is searching for buried treasure.
The giant, man-eating Graboids are back and even deadlier than before, terrorizing the inhabitants of a South African wildlife reserve as they attack from below-and above.
Burt Gummer (Michael Gross) and his son Travis Welker (Jamie Kennedy) find themselves up to their ears in Graboids and Ass-Blasters when they head to Canada to investigate a series of deadly giant-worm attacks. Arriving at a remote research facility in the artic tundra, Burt begins to suspect that Graboids are secretly being weaponized, but before he can prove his theory, he is sidelined by Graboid venom. With just 48 hours to live, the only hope is to create an antidote from fresh venom — but to do that, someone will have to figure out how to milk a Graboid!